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Exosomes Derived From Dendritic Cells Infected With Toxoplasma gondii Show Antitumoral Activity in a Mouse Model of Colorectal Cancer

Pathogen-based cancer therapies have been widely studied.Parasites, such as Toxoplasma gondii have elicited great interest in cancer therapy.Considering safety in clinical applications, we tried to develop an exosome-based immunomodulator instead of a live parasite for tumor treatment.The exosomes, called DC-Me49-exo were isolated from culture supe

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Diagenetic evolution of key minerals and its controls on reservoir quality of Upper Ordovician Wufeng-Lower Silurian Longmaxi shale of Sichuan Basin

Based on core, thin section, scanning electron microscopy observations, X-ray diffraction analysis, as well as carbon and oxygen isotopes and energy spectrum analysis of carbonate rocks, the quartz, feldspar, pyrite, carbonate and clay minerals in shale of the Upper Ordovician Wufeng-Lower Silurian Longmaxi formations of Sichuan Basin were effectiv

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